QSER1 protects DNA methylation valleys from de novo methylation. Dixon G, Pan H, Yang D, Rosen BP, Jashari T, Verma N, Pulecio J, Caspi I, Lee K, Stransky S, Glezer A, Liu C, Rivas M, Kumar R, Lan Y, Torregroza I, He C, Sidoli S, Evans T, Elemento O, Huangfu D. Science. 2021 Apr 9;372(6538):eabd0875. doi: 10.1126/science.abd0875. PMID: 33833093
Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency. Li QV, Rosen BP, Huangfu D. Wiley Interdiscip Rev Syst Biol Med. 2020 Jan;12(1):e1464. doi: 10.1002/wsbm.1464. Epub 2019 Aug 13. PMID: 31407519
Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation. Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh CL, Yang D, Crespo M, Shukla A, Xiang Q, Dündar F, Zumbo P, Witkin M, Koche R, Betel D, Chen S, Massagué J, Garippa R, Evans T, Beer MA, Huangfu D. Nat Genet. 2019 Jun;51(6):999-1010. doi: 10.1038/s41588-019-0408-9. Epub 2019 May 20. PMID: 31110351
Glutamine independence is a selectable feature of pluripotent stem cells. Vardhana SA, Arnold PK, Rosen BP, Chen Y, Carey BW, Huangfu D, Carmona Fontaine C, Thompson CB, Finley LWS. Nat Metab. 2019 Jul;1(7):676-687. doi: 10.1038/s42255-019-0082-3. Epub 2019 Jul 8. PMID: 31511848
MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling. Mellios, N, Feldman, D, Sheridan, SD, Ip, JPK, Kwok, S, Amoah, S, Rosen, B, Rodriguez, B, Crawford, B, Swaminathan, R, Chou, S, Li, Y, Ziats, M, Ernst, C, Jaenisch, R, Haggarty, S, Sur, M. Molecular Psychiatry. 2017. PMID: 28439102
Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes. Zhu Z, Li QV, Lee K, Rosen BP, González F, Soh CL, Huangfu D. Cell Stem Cell. 2016 Jun 2;18(6):755-68. doi: 10.1016/j.stem.2016.03.015. PMID: 27133796
Sphingosine kinase 1 is regulated by peroxisome proliferator-activated receptor α in response to free fatty acids and is essential for skeletal muscle interleukin-6 production and signaling in diet-induced obesity. Ross JS, Hu W, Rosen B, Snider AJ, Obeid LM, Cowart LA. J Biol Chem. 2013 Aug 2;288(31):22193-206. doi: 10.1074/jbc.M113.477786. PMID: 23766515