Cancer Biology & Genetics Program

The Christine Mayr Lab

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Research

Christine Mayr, MD, PhD

My laboratory studies how mRNA elements that do not encode amino acids contribute to the regulation of biological complexity. We examine how 3′ untranslated regions (3′UTRs) regulate protein functions without affecting protein abundance. We also investigate the role of mRNAs as cytoplasmic organizers that enable subcellular compartmentalization required for the implementation of protein functions.

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Research Projects

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Christine Mayr lab

Featured News

In the Lab
3D organelle
This Newly Discovered Organelle Is Fierce

It’s not every day that scientists discover a new part of the cell. Two biologists from the Sloan Kettering Institute just did.
In the Lab
Sloan Kettering Institute molecular biologist Christine Mayr
Scientists Find Cancer Drivers Hiding in a New Place

New findings from researchers at the Sloan Kettering Institute suggest that cancer causes may be lurking in the molecule that bridges DNA and protein.
Cancer Biologist Christine Mayr
At Work: Cancer Biologist Christine Mayr

Christine Mayr, who once dreamed of exploring space as an astronaut, today probes new realms in the field of cancer genetics.

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Publications

Ma W, Mayr C. A membraneless organelle associated with the endoplasmic reticulum enables 3′UTR-mediated protein-protein interactions. Cell 175, 1492-1506 (2018).

Berkovits BD, Mayr C. Alternative 3’UTRs act as scaffolds to regulate membrane protein localization. Nature 522, 363-367 (2015). Epub 2015 Apr 20.

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People

Christine Mayr

Christine Mayr, MD, PhD

  • Molecular and cell biologist Christine Mayr studies how 3′UTRs regulate protein functions and how mRNAs contribute to cytoplasmic organization.
  • MD, Free University Berlin
  • PhD, Humboldt University Berlin
mayrc@mskcc.org
Email Address
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Members

Shih-Han (Peggy) Lee
Shih-Han (Peggy) Lee

Postdoctoral Fellow

Xiuzhen Chen
Xiuzhen Chen

Postdoctoral Fellow

Mervin Fansler
Mervin Fansler

PhD student, Tri-I PhD Program in Computational Biology & Medicine

Ellen Horste
Ellen Horste

Graduate Student

Buki Kwon
Buki Kwon

Postdoctoral Fellow

Federica Lari
Federica Lari

Postdoctoral Fellow

Weirui Ma
Weirui Ma

Postdoctoral Fellow

Sibylle Mitschka
Sibylle Mitschka

Postdoctoral Fellow

Neil Robertson
Neil Robertson

Postdoctoral Fellow

Gang Zhen
Gang Zhen

Postdoctoral Fellow

Pia Worrell
Pia Worrell

Administrative Assistant

Lab Alumni
Steve Lianoglou

Graduate Student

Irtisha Singh
Irtisha Singh

Graduate Student, Tri-I CBM Program

Eric Kallin
Eric Kallin

Postdoctoral Fellow

Binyamin Berkovits
Binyamin Berkovits

Postdoctoral Fellow

Marie Clemot
Marie Clemot

Master Student

Omar Hamdani, MPH
Omar Hamdani

Research Technician

Jessica Johnson
Jessica Johnson

Research Technician

Vidur Garg
Vidur Garg

Research Technician

Neil Patel, Medical School
Neil Patel

Research technician

Jihye (Sophia) Lee
Jihye (Sophia) Lee

Research Technician

Sarah Tisdale
Sarah Tisdale

Postdoctoral Fellow

Lab Affiliations

Achievements

  • Luise and Allston Boyer Young Investigator Award for Basic Research (2019)
  • NIH Director’s Pioneer Award (2016)
  • Pershing Square Sohn Prize for Young Investigators in Cancer Research (2015)
  • Damon Runyon-Rachleff Innovation Award, Damon Runyon Cancer Research Foundation (2012)

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Christine Mayr discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2020 through disclosure submission in spring 2021). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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