Daniel Stephen

Senior Research Technician

The Alexandra Joyner Lab
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Daniel Stephen

Senior Research Technician

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Daniel Stephen

Office Phone

212-639-3980

Office Fax

212-717-3738

Email

stephed1@mskcc.org

Research Interests & Responsibilities

I have been a member of the Joyner Lab since July 2000. Previously, I worked at Beth Israel Medical Center in Boston, MA. My primary responsibilities include maintaining mouse lines and assisting post-docs with a variety of techniques. In addition, I help maintain laboratory equipment.

Publications

Bai, C. B., Auerbach, W., Lee, J., Stephen, D., and Joyner, A.L. (2002). Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the SHH pathway. Development, 129: 4753-4761.

Weiner, H.L., Hurlbert, M.S., Bakst, R., Ruggiero, J., Ahn, E., Lee, W.S., Stephen, D., Zagzag, D., Joyner, A.L., and Turnbull, D.H. (2002). Induction of medulloblastomas in mice by Shh, independent of Gli1. Cancer Research, 62: 6385-6398.[PMID:12438220}

Bai, C.B., Stephen, D., and Joyner, A.L. (2004). All mouse ventral spinal cord patterning by Hedgehog is Gli dependent and involves an activator function of Gli3. Developmental Cell, 6: 103-115.

Kimura, H., Stephen, D., Joyner A.L. and Curran, T. (2005) Gli1 is important for medulloblastoma formation in Ptc1+/- mice. Oncogene, 24: 4026-4036.

Sgaier, S.K., Lao, Z., Villanueva, M.P. Berenshteyn, F., Stephen, D., Turnbull, R.K., and Joyner, A.L. (2007) Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to the dosage of Engraield genes. Development. 2007 Jun;134(12):2325-35.