Molecular Biology Program

The Iestyn Whitehouse Lab

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Research

Iestyn Whitehouse, PhD
Interim Director of the Center for Epigenetics Research (CER)

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on understanding basic mechanisms and use a combination of biochemical, molecular biological and genomics approaches. We like to develop new technology and are particularly interested in the development and application of single molecule technologies such as Nanopore sequencing and single molecule indexing strategies.

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Research Projects

The Iestyn Whitehouse Lab

Featured News

Molecular Biologist Iestyn Whitehouse
At Work: Molecular Biologist Iestyn Whitehouse

Iestyn Whitehouse translated an early interest in woodworking into a career as a molecular biologist focused on the human genome's building blocks.
Video
Pictured: Major Trends in Modern Cancer Research Seminar
Watch Videos from 2011 Major Trends in Modern Cancer Research Seminar

Hundreds of high school students and teachers attended our sixth annual Major Trends in Modern Cancer Research seminar to learn about cutting-edge biomedical research and to engage with leading scientists.
Recipients of the Louis V. Gerstner, Jr. Young Investigators Fund, pictured with Mr. Gerstner. (From left) Iestyn Whitehouse, Hans-Guido Wendel, Mr. Gerstner, Stephen Long, and Timothy Chan.
Memorial Sloan Kettering Names First Gerstner Fund Recipients

Memorial Sloan Kettering has announced the creation of the Louis V. Gerstner, Jr. Young Investigators Fund and has named the fund's first four recipients.

Publications

High-resolution mapping of DNA replication dynamics in S. cerevisiae. McGuffee S, Smith D, Whitehouse I. Manuscript in preparation.

Intrinsic Coupling of Lagging Strand Synthesis to Chromatin Assembly. Smith D, Whitehouse I. Nature, 2012. In press.

ATRX: Put me on repeat. Whitehouse I, Owen-Hughes T. Cell. 2010 Oct 29;143(3):335-6. (Review)

Chromatin remodeling around nucleosome-free regions leads to repression of noncoding RNA transcription. Yadon AN, Van de Mark D, Basom R, Delrow J, Whitehouse I, Tsukiyama T. Mol Cell Biol. 2010 Nov;30(21):5110-22. Epub 2010 Aug 30.

Opening windows to the genome. Whitehouse I, Tsukiyama T. Cell. 2009 May 1;137(3):400-2. (Review)

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People

Iestyn Whitehouse, PhD

Iestyn Whitehouse, PhD

Interim Director of the Center for Epigenetics Research (CER)

  • Molecular biologist Iestyn Whitehouse investigates chromatin structure and the function of ATP-dependent chromatin remodelling enzymes.
  • PhD, The University of Dundee
whitehoi@mskcc.org
Email Address
212-639-8398
Office Phone

Members

Jennifer A Yavid

Research Technician

Clémence Claussin
Clémence Claussin

Postdoctoral Fellow

Axel Delamarre
Axel Delamarre

Postdoctoral Fellow

Nickolas Almodovar

Graduate Student

Lab Alumni
Lisbelle Adorno

Administrative Assistant

Jieqing (Jenny) Jiang

Graduate Student

Sean McGuffee

Postdoctoral Fellow

Nicolas Nocetti

Graduate Student

Duncan Smith

Postdoctoral Fellow

Tejas Yadav

Graduate Student

James Bellush
James Bellush

Graduate Student

Jessica Fyodorova
Jessica Fyodorova

Research Technician

Ehsan Pourkarimi
Ehsan Pourkarimi

Postdoctoral Fellow

Lab Affiliations

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Iestyn Whitehouse discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2020 through disclosure submission in spring 2021). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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