Cancer Biology & Genetics Program
The Joan Massagué Lab
Research
We are interested in metastasis, the cause of 90% of cancer deaths. The lab investigates metastatic stem cells and their stromal niches. The role of immune regulatory and regenerative signals, particularly TGF-β, is of interest. General as well as organ-specific mediators of metastasis are under investigation. We are defining the phenotypic plasticity and evolution of metastatic cell populations from dormancy to outbreak, identifying drug targets, and enabling clinical trials to treat metastasis.
Inside My Lab: Joan Massagué
Featured News
People
Joan Massagué, PhD
Member, Cancer Biology & Genetics Program; Marie-Josée and Henry R. Kravis Foundation Chair; Director, Sloan Kettering Institute
- Joan Massagué studies the control of stem cell growth and phenotype in tumor progression, metastasis, and response to therapy.
- PhD, University of Barcelona
- j-massague@ski.mskcc.org
- Email Address
- 646-888-2044
- Office Phone
Members
Senior Research Assistant
Sr. Research Scientist
GSK, Graduate Student
Sr. Research Scientist
SKI, Admin. Assistant II
Postdoctoral Researcher
Research Assistant
Research Fellow
Research Scholar
Research Scholar
Research Technician
Sr. Executive Assistant
Research Scholar
Research Associate
Tri-I PhD, CBM, Graduate Student
Lab Alumni
Medical Student Mount Sinai
Assistant Professor, Tsinghua University, Beijing
Assistant Professor- University of Illinois, Chicago
Assistant Member, Molecular Pharmacology Program, SKI; Department of Medicine
Medical Student, Stanford, CA
Internal Medicine Resident at Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Senior Research Assistant
Group Leader, Accutar Biotech
Research Investigator @ Biomarker Discovery, Beijing, China
Assistant Professor, Shanghai Jiao Tong University, China
Assistant Professor of Pathology & Cell Biology, Columbia University
Assistant Professor, Yale University
Supervisory Patent Examiner, US Patent & Trademark Office
Director of Preclinal Research, Vall d'Hebron Institute of Oncology, BCN
Chair, Biochemistry, University of Toronto
Director Veterinary Clinical Biochemistry, University of Barcelona
Associate Professor, SUNY Downstate Medical Center
Neuro-Oncologist / MSK HOPP Program
Assistant Professor, Virginia Commonwealth University
Associate Professor, Yale University
Volunteer and Research Assistant, University of Arizona
Counselor of Citizens in the District, Barcelona Spain
Principle Scientist, Eli Lilly and Company, New York
EVP, Director of Medical and Scientific Affairs at DDB Health
Professor, University of Toronta
Senior Director, ArQule Inc.
Assistant Professor, The Wistar Institute, Philadelphia, PA
Professor, Tsinghua University, Beijing
Associate Professor; Chief Integration Officer and Deputy Chief Medical Officer, Smilow Cancer Network, Yale
Staff Scientist, Albert Einstein College of Medicine, NY
Assistant Professor, Tsinghua University, Beijing, China
Consultant in Immuno-oncology
Associate Director, Clinical Biomarkers, Bristol-Myers Squibb
Member, Pediatric Oncology & Hematology, Columbia University
Member, Institut de Recerca Biomedica, Barcelona
Senior Clinical Research Associate at Veracyte, Inc.
Assistant Professor, U. North Carolina
Professor, Cardiovascular Research Institute, UCSF
Chief Scientific Officer at Accutar Biotec
Professor & Chair, Dept Biochemistry, U. Turku, Finland
Professor of Pathology, Columbia University
Assistant Professor, University of Massachusetts Medical School
Scientist II, Biology at BluePrint Medicines
Head, Tumor Immunotherapy, Seres Therapeutics
Assistant Professor, Westlake University, China
Professor of Molecular Biology, Princeton University
Assistant Professor, KAIST, Korea
Head of Intellectual Property, Molecular Partners AG; Switzerland
Professor of Radiation Oncol, Johns Hopkins School of Medicine
Graduate Student @ Columbia University
Assistant Professor, Cornell University
Patent Attorney, Novartis
Research Technician
Assoc. Professor of Mol. Cell. Oncology, MD Anderson Cancer Center
Research Scholar
Associate Member, Rutgers Cancer Institute, NJ
Professor, Baylor College of Medicine, Houston
Professor, Universidad Nacional Autonoma de Mexico
University of Oviedo, Spain
Senior Medical Director at AbbVie, Chicago
Student, St. Joseph's Seminary, Washington
Assistant Professor of Pathology, UT Southwestern Med, Dallas
EVP, Director of Medical & Scientific Services at Chameleon Communications International
Assistant Professor of Radiation Oncology, U. Pennsylvania
Biocat Director of Healthcare Programs
Associate Professor of Pathology, Yale University
Group Leader, (IMP) Institute of Molecular Pathology, Austria
Corporate Officer, VP Business Dev.& Licensing, Daiichi Sankyo Co. Ltd, Tokyo
Group Leader, German Cancer Research Center
Assistant Professor, UCLA
Professor, CSIC, Salamanca
Director, Wake Forest School of Medicine
Professor, Dana-Farber Cancer Institute, Harvard University
Research Director, CNRS and Institute Curie, Paris
Management, Integrated Bioscience Solutions, LLC
Principal Investigator, Landspitali University Hospital; University of Iceland
Professor of Cancer Research, Lund University, Sweden
Program Leader, University of Dundee, UK
Research Director, Vall Hebron Institute of Oncology, Barcelona
Student, Stony Brook University
Assoc. Professor of Biochemistry & Medicine, McGill University
Partner at Carter, DeLuca, Farrell & Schmidt, LLP
Professor, Rockefeller University, New York
Professor, Consejo Superior de Investigactiones Cientificas, Madrid
Staff Scientist, Hoffmann-La Roche Inc.
Associate Professor, Dept. of Surgery, Rutgers University, NJ
Group Leader, CNIO, Madrid
Program Leader, Medical Research Council (MRC), U. Cambridge
Professor, University of Barcelona School of Medicine
Professor, Universite de Caen, France
Staff Scientist, Hoffman-La Roche, Inc.
Genetic Counselor, Peter MacCallum Cancer Institute, Australia
Associate Laboratory Member, Research Facilities @ MSKCC
Associate Professor of Medicine, University of Vienna, Austria
Assoc. Professor of Biochemistry, University of Virginia
Senior Investigator, Lunenfeld Research Institute, U. Toronto
Assistant Professor, Tsinghua University, Beijing
Director, Biology at Foghorn Therapeutics
Chief Editor, Nature Cancer @ Nature Publishing
Professor, Universidad Nacional Autonoma de Mexico
Professor, Baylor College of Medicine, Houston
Assistant Professor, Westlake University, China
Lab Affiliations
Achievements
- Director, Sloan Kettering Institute (2014–)
- HHMI Scientific Review Board (2014–)
- HHMI Investigator (1990-2013)
- Fellow, American Association for Cancer Research (AACR) Academy (2016)
- Pezcoller Foundation-AACR International Award for Cancer Research (2016)
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- Charles Rodolphe Brupbacher Prize for Cancer Research (2015)
- National Prize for Research in Biology, Spain (2014)
- American Italian Cancer Foundation Price (2013)
- Prize in Cancer Research, Robert J. and Claire Pasarow Foundation (2011)
- Frontiers Prize in Biomedicine, BBVA Foundation (2008)
- Vilcek Prize, Vilcek Foundation (2006)
- Member, Institute of Medicine (2006)
- Award in Science and Technology, Prince Asturius Foundation (2004)
- Member, National Academy of Sciences (2000)
- Member, American Academy of Arts and Sciences (1999)
- Investigator, Howard Hughes Medical Institute (1990)
- Elucidation of the TGF-beta pathway
Lab News & Events
Accolades
Team Recognitions
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Welcome to the Massague Lab : Elena Spina arrived in August from University of Calabria.
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Welcome to the Massague Lab: Kenta Kawasaki arrived in October from Keio University School of Medicine.
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Welcome to the Massague Lab: Dylan Manuele arrived in June from the University of Rochester.
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Congratulations: Our first in person lab meeting for 2021!
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The Massague Lab celebrates the arrival of Zhenghan Wang’s daughter Everly!
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Farewell: Weiping Shu has retired from the Massague lab after many years of fantastic service as a senior research technician. Thank you Weiping for all your contributions!
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Congratulations: Harihar Basnet who departed in February as Assistant professor in the Department of Basic Medical Sciences at Tsinghua University
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Welcome: Sayyed Hamed Shahoei who joined in November from University of Illinois at Urbana-Champaign
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Congratulations : Lin Tian who departed in November as research investigator at the division of Biomarker Discovery, Shanghai China
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Welcome to the Massague Lab: Lila Peters arrived in July from the University of Michigan
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Congratulations: George Lampe departed in July to Graduate School at Columbia University.
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Welcome to the Massague Lab: Jun Ho Lee joined in May from UNIST, Uslan, Republic of Korea
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Welcome to the Massague Lab: Jin Suk Park joined in March from University of Texas Southwestern Medical Center, Dallas
Dr. Massague invited the postdocs to his home for an annual gathering.
In October 2021, A small birthday celebration was held for Gabi.
The Massague Lab had the pleasure to attend a summer happy hour cruise! It was a wonderful time!
The Massague Lab attending their Friday Lab Meetings!
The Massague Lab celebrates the arrival of Zhenghan Wang’s daughter Everly!
Happy Birthday Joan !
Happy Birthday Joan: Post Doc Jin Suk Park playing the clarinet for Joan’s Birthday!
Farewell: Weiping Shu has retired from the Massague lab after many years of fantastic service as a senior research technician. Thank you Weiping for all your contributions!
In June 2019, we bid a farewell to one of our Research Techs, Jessica Hampton. Jessica will be leaving to attend Med school at Stanford University. The Massague Lab wishes her well in all of her future endeavors
March 2019 - Paper Published. During metastasis, cancer cells spread to distant organs where they divide to form microscopic clusters, or micrometastases, that can grow into new tumors. Identification of genes activated in micrometastases can reveal therapeutic targets that can kill cancer cells before they grow into larger tumors that are harder to treat.
The Massague Lab came together to celebrate Dr. Massague's Birthday
The Massague Lab came together to wish Dr. Massague a Happy Birthday!
The Massague Lab at Holiday Party
