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Sloan Kettering Institute
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- Sloan Kettering Institute
- Research
  - - Programs & Centers
    - Sloan Kettering Institute
      Pursuing basic and translational research across 9 programs and 100+ labs
    - Memorial Hospital research
      Focusing on clinical cancer research and population health
    - Human Oncology & Pathogenesis Program (HOPP)
      Bridging the lab and the clinic through translational research
    - Collaborative research centers
      Fostering interdisciplinary collaborations between laboratory scientists and clinicians
    - Extramural collaborations
      Partnering with other academic and research institutions
  - - Research at MSK
    - Our research impact
    - Research topics
    - Core facilities & resources
      Offering state-of-the-art resources for our researchers
    - Find a researcher or lab
    - Education & training programs
- Education & Training
  - - For Research
    - Postdoctoral training
    - Gerstner Sloan Kettering Graduate School of Biomedical Sciences
      Offering a curriculum with a focus on cancer
    - PhD & MD/PhD programs
    - MSK Bridge program
      Connecting college seniors to future careers in biomedicine
    - High school & undergraduate summer programs
- Careers
- MSK Direct
- - - In the U.S.
    - English
    - Español
    - Pу́сский
    - Outside of the U.S.
    - العَرَبِيَّة
    - Deutsch
    - English
    - Español
    - 한국어
    - עִבְרִית
    - Italiano
    - Português
    - Pу́сский
    - Türkçe
    - 中文

Minna Balbas, PhD

Senior Manager, Clinical Science, Loxo Oncology at Lilly, San Francisco, CA

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Minna Balbas

Lab Phone

646-888-2163

Lab Fax

646-888-2595

Email

balbasm@sloankettering.edu

Dissertation

Mutation Based Resistance to Antiandrogens in Prostate Cancer (2013)

Mentor

Charles L. Sawyers, MD

Start Year

2009

End Year

2013

Education

University of California, Los Angeles

Publications

Balbas MD, Burgess MR, Murali R, Wongvipat J, Skaggs BJ, Mundel P, Weins A, Sawyers CL. (2014) MAGI-2 scaffold protein is critical for kidney barrier function. Proc Natl Acad Sci U S A., 111, 14876-81. PMCID: PMC4205655.

Arora V, Schenkein E, Murali R, Subudhi S, Wongvipat J, Balbas M, Shah N, Cai L, Efstathiou E, Logothetis C, Cheng D, Sawyers C. (2013) Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade. Cell, 155, 1309-1322.

Balbas M, Evans M, Hosfield D, Wongvipat J, Arora V, Watson P, Chen Y, Greene G, Shen Y, Sawyers C. (2013) Overcoming mutation-based resistance to antiandrogens with rational drug design. Elife, 2, 1-21.

Watson P, Chen Y, Balbas M, Wongvipat J, Socci N, Viale A, Kim K, Sawyers C. (2010) Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor. Proc Natl Acad Sci U S A, 107, 16759-16765.

Shah NP, Kasap C, Weier C, Balbas M, Nicoll JM, Bleickardt E, Nicaise C, Sawyers CL. (2008) Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis. Cancer Cell 14, 485-93.