The Center has dedicated biostatisticians who focus on large observational data analyses using sophisticated inferential methods to develop and test hypotheses related to the quality of cancer care in the United States. Datasets frequently employed include the SEER-Medicare data, indemnity Medicare data parts A, B, and D, the National Cancer Database, primary data underlying clinicaltrials.gov, the Nationwide Inpatient Sample, Blue Health Intelligence, as well as institutional encounter data and payment rate crosswalk data. These statisticians also provide institutional support for analyses of care redesign at Memorial Sloan Kettering that incorporate normalized cost and resource utilization data.