John Petrini: Publications

Hohl, M., Mojumar, A., Hailemariam, S. Kuryavi, V., Ghisays, F., Sorenson, K., Chang, M., Taylor, B.S., Patel, D., Burgers, P.M., Cobb, J.A., Petrini, J.H. (2020) Modeling Cancer Genomic Data in Yeast Reveals Selection Against ATM Function During Tumorigenesis. PLos Genet., 16 (3): e1008422

Wu, W., Bhowmick, R., Vogel, I., Ozer, O., Ghisays, F., Thakur, R.S., Sanchez De Leon, E., Richter, P.H., Ren, L., Petrini, J.H., Hickson, I.D., Liu, Y., (2020) RTEL1 Suppresses G-quadruplex-Associated R-Loops at Difficult-to-Replicate Loci in the Human Genome. Nat Struct Mol Biol. 27. 424-437

Kim, JH., Penson, A.V., Taylor, B.S., Petrini, J.H., (2019) Nbn-Mre11 interaction is required for tumor suppression and genomic integrity. 2019:201905305. doi: 10.1073/pnas. 1905305116. Proc Natl Acad Sci. PMC6660787

Park YB, Hohl, M., Padjasek, M., Jeong, E., Kyeong J.S., Kretzel, A., Petrini, J.H., Cho, Y., (2017) Eukaryotic Rad50 Functions as a Rod-shaped Dimer. Nat Struct Mol Biol (3) 248-257 PMC5625350

Kim, JH., Grosbart, M., Anand, R., Wyman C., Cejka, P., Petrini, J.H., (2017) The Mre11-Nbs1 interface is essential for viability and tumor suppression. Cell Rep. 18. (2) 496-507 PMC5234850

Hohl, M., Kochanczyk, T., Tous, C., Aguilera, A., Krezel, A. Petrini, J.H. (2015) Interdependence of the Rad50 hook and globular domain functions. Mol. Cell. 57: 479-491. PMC4527088

Al-Ahmadie, H., Iyer, G., Hohl, M., Inagaki, A., Shultz N., Hanrahan, AJ., Scott, S.N., Brannon, A.R., McDermott, G.C., Pirun, M., Ostrovnaya, I., Kim, P., Socci, N.D., Viale, A., Schwartz, G.K., Reuter, V., Bochner, B.H., Rosenberg, JE., Bajorin, DF., Berger, M.F., Petrini, J.H., Solit, D.B., Taylor, B.S. (2014) Synthetic lethality in ATM-deficient RAD50-mutant tumors underlie outlier response to cancer therapy. Cancer Discov. 9. 1014-1021 PMC4155059

Ballew, B., Joseph, V., De, S., Sarek, G., Vannier, J-B., Stracker, T., Schrader, K.A., Small, T.N., O’Reilly, R., Manschreck, C., Harlan Fleischut, M.M., Sullivan, J., Stratton, K., Yeager, M., Jacobs, K., Giri, N., Alter, B.P., Boland, J., Burdett, L., Offit, K., Boulton, S., Savage, S.A., Petrini, J.H. (2013) A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, RTEL1, Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome. PLoS Genet, 8.: e1003695 PMC3757051

Gupta, G., Vanness, K., Barlas, A., Manova-Todorova, K., Wen, Y.H., Petrini, J.H. (2013) The Mre11 Complex Suppresses Oncogene-driven Breast Tumorigenesis and Metastasis. Mol Cell 52. 353-365 PMC3902959