William T. Yewdell, Youngjun Kim, Priyanka Chowdhury, Colleen M. Lau1, Ryan M. Smolkin, Kalina T. Belcheva, Keith C. Fernandez, Montserrat Cols, Wei-Feng Yen, Bharat Vaidyanathan, Davide Angeletti, Adrian B. McDermott, Jonathan W. Yewdell, Joseph C. Sun, Jayanta Chaudhuri. (2020) A hyper-IgM syndrome mutation in AID disrupts G-quadruplex binding and chromatin localization. Immunity (In Press).
Angeletti, D., I. Kosik, J. J. S. Santos, W. T. Yewdell, C. M. Boudreau, V. V. A. Mallajosyula, M. C. Mankowski, M. Chambers, M. Prabhakaran, H. D. Hickman, A. B. McDermott, G. Alter, J. Chaudhuri, and J. W. Yewdell. (2019) Outflanking immunodominance to target subdominant broadly neutralizing epitopes. Proc Natl Acad Sci USA 116: 13474-13479. PMCID: PMC6986270
Pucella JN, Cols M, Yen W-F, Xu S and Chaudhuri J. The B cell activation induced miR-183 cluster plays a minimal role in canonical primary humoral responses. (2019) J. Immunology; 202(5): 1383-1396. PMCID: PMC6986270
Nicolas L, Cols M, Smolkin R, Fernandez KC, Yewdell WT, Yen W-F, Zha S, Vuong B and Chaudhuri J. ATM influences germinal center integrity.(2019) Cutting Edge: Journal of Immunology; 202 (11): 3137-3142. PMCID: PMC6529280
Yen W-F, Sharma R, Cols M, Lau CM, Chaudhry A, Chowdhury P, Yewdell WT, Vaidyanathan B, Sun A, Coffre M, Pucella JN, Chen C-C, Jasin M, Sun JC, Rudensky AY, Koralob SB and Chaudhuri J. (2019). Distinct requirements of CHD4 during B cell development and antibody response. Cell Reports 27(5):1472-1486. PMCID: PMC6527137
Vaidyanathan B, Chaudhry A, Yewdell WT, Angeletti D, Yen WF, Wheatley AK, Bradfield CA, McDermott AB, Yewdell JW, Rudensky AR, Chaudhuri, J. The aryl-hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med 2017 214: 197-20
Yen WF, Chaudhry A, Vaidyanathan B, Yewdell WT, Pucella JN, Sharma R, Liang Y, Li K, Rudensky AY, Chaudhuri J. BRCT-domain protein BRIT1 influences class switch recombination. Proc Natl Acad Sci USA 2017; 114: 8354-8359.
DiMenna LJ, Yen WF, Nicolas L, Sharma R, Saldanha ZN, Chaudhuri J. The transcription factor Sox2 regulates AID expression in class-switched B cells. Cutting Edge: J Immunol 2017; 198: 2244-2248.
Kunimoto H, McKenney AS, Meydan C, Shank K, Nazir A, Rapaport F, Durham B, Garrett-Bakelman FE, Pronier E, Shih AH, Melnick A, Chaudhuri J, Levine RL. Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells. Blood. 2017; 129:1779-1790.
Zheng S, Vuong BQ, Vaidyanathan B, Lin JY, Huang FT, Chaudhuri J. Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA. Cell. 2015; 161: 762-73.
Pucella JN, Yen WF, Kim MV, van der Veeken J, Luo CT, Socci ND, Naito Y, Iwai, N, Chaudhuri J. miR182 is largely dispensable for adaptive immunity: lack of correlation between expression and function. J Immunol. 2015; 194: 2635-42.
Matthews AJ, Husain S, Chaudhuri J. Binding of AID to DNA does not correlate with mutator activity. J Immunol. 2014; 193: 252-7.
Vuong BQ, Herrick-Reynolds K, Vaidyanathan B, Pucella JN, Ucher AJ, Donghia NM, Gu X, Nicolas L, Nowak U, Rahman N, Strout MP, Mills KD, Stavnezer J, Chaudhuri J. A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination. Nat Immunol. 2013; 14: 1183-9.
Review Articles
Matthews AJ, Matthews AJ, Zheng S, DiMenna LJ, Chaudhuri J. Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair. Adv Immunol. 2014; 122:1-57.
Yewdell WT, Chaudhuri J. A transcriptional serenAID: the role of noncoding RNAs in class switch recombination. Int Immunol. 2017; 29:183-196.